Baylor College of Medicine

education 📍 Houston, United States
2
EM Publications
4
EM Researchers

Associated Institutions

Houston Methodist
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Michael E. DeBakey VA Medical Center
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Memorial Hermann Institute for Rehabilitation and Research Foundation
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Texas Medical Center
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The University of Texas MD Anderson Cancer Center
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Publications

Prevalence of erythromelalgia in the United States: a cross-sectional study using the All of Us database.

Sidiq SA, Asad U, Ren V
Archives of dermatological research

Erythromelalgia is a rare condition with no published estimates of prevalence from a diverse, nationwide cohort of American patients. We performed a cross-sectional analysis of the All of Us database to estimate the prevalence of erythromelalgia overall and by age groups. Of 410,361 participants, 47 were diagnosed with erythromelalgia, representing an overall age-adjusted prevalence of 10.3 (95% CI 7.4-13.3) per 100,000 people. The prevalence was higher in the 65 + age group (16, 95% CI 9.5-23, per 100,000 people) than the less than 65 age group (9.1, 95% CI 5.5-13, per 100,000 people). Further studies are needed to determine the burden of erythromelalgia in specific subgroups, such as race, within the United States.

Erythromelalgia involving the face.

Gilmore RR, Applebaum DS, Parsons JL, Hsu S
Dermatology online journal

Erythromelalgia is a rare disorder characterized by burning pain, erythema, and increased temperature typically involving the distal extremities. Although it can progress to involve the face, erythromelalgia presenting only on the face is particularly rare. This disorder is often misdiagnosed when it presents on the extremities and is even more likely to be misdiagnosed when presenting only on the face, delaying appropriate treatment and causing considerable frustration for the patient. We report a case of a 26-year-old woman with erythromelalgia that involved only the face for a number of years and was treated unsuccessfully as rosacea, seborrheic dermatitis, and contact dermatitis. She subsequently developed involvement of the ears and hands in the more typical distribution of erythromelalgia. We discuss the differential diagnosis of erythromelalgia involving the face and extremities, the proposed pathogenesis and management of the disorder, and the psychological distress this condition can cause. Even when the correct diagnosis of erythromelalgiais made, treatment is difficult, with no single therapy consistently effective.