Chongqing Medical University

education 📍 Chongqing, China
OpenAlex Profile Wikipedia
2
EM Publications
7
EM Researchers

Associated Institutions

Second Affiliated Hospital of Chongqing Medical University
related
Stomatological Hospital of Chongqing Medical University
related
People's Hospital of Bishan District
related
The Affiliated Yongchuan Hospital of Chongqing Medical University
related
Children's Hospital of Chongqing Medical University
related

Erythromelalgia Researchers

Yang X
2 EM publications • h-index: 3
Chen S
2 EM publications • h-index: 1
Duan G
1 EM publication • h-index: 20
Zuo L
1 EM publication • h-index: 3
Su A
1 EM publication • h-index: 3
Shi Y
1 EM publication • h-index: 8
Li N
1 EM publication • h-index: 19

Publications

Genetic and Clinical Insights into Inherited Erythromelalgia: A Comprehensive Review of Cases from China and Worldwide.

Li Y, He Z, Liu Y, Duan G, Li Z , et al.
The Journal of investigative dermatology •

Recent genomic research has identified variants in the SCN9A gene as a key factor in inherited erythromelalgia (IEM) pathogenesis. In this review, data are collected and analyzed to identify SCN9A sequence variants associated with IEM, demographic patterns, and treatment responses among patients. We describe a spectrum of SCN9A variants associated with IEM. Sex and age distributions among patients with IEM show a predominance of cases with clinical onset before the age of 10 years, whereas sex differences are not pronounced. Some patients with specific pathogenic variants respond to pharmacotherapy, such as p.L858F/H (mexiletine) and V400M, S241T, and I234T (carbamazepine), suggesting potential for personalized therapeutic approaches.

View on PubMed → DOI →

Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia.

Zuo L, Su A, Shi Y, Li N, Chen S , et al.
Frontiers in neurology •

In children, erythromelalgia is a rare chronic pain syndrome characterized by erythema, severe burning pain, and itching of affected feet. Unfortunately, there is no definitive therapy available currently. Here, we report a case of primary erythromelalgia and the treatment response in a 10-year-old boy, whose genetic findings for mutations in the SCN9A gene were positive and skin biopsy results were diagnosed as small fiber neuropathy, while he has suffered from excruciating burning pain, itching, erythema, and recurrent infections over the past 3 years. He did not respond well to conventional treatment, and the only way to receive minimal relief was to immerse his feet in ice water. After a successful trial of spinal cord stimulation (SCS), the implantable pulse generator (IPG) was successfully implanted without complications, and it proved partial response to therapy. There is no specific, efficient treatment for pediatric erythromelalgia currently, but this case demonstrates neuromodulation serves as part of the multimodal regimen to treat pediatric erythromelalgia.

View on PubMed → DOI →